VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Role of lipid peroxides in the pathogenesis of arteriosclerosis. Detoxication of lipid peroxides by the glutathione-peroxidase system in the aorta

   
Lankin V.Z., Gurevich S.M., Kotelevtseva N.V., Tikhaze A.K., Gerasimova E.N.
PubMed Id: 16399
Year: 1976  Volume: 22  Issue: 3  Pages: 392-395
In aorta of intact rabbits the high activity of glutathione-peroxidase, which detoxicates lipoperoxides, was observed. In aorta of animals with pronounced experimental atheromatosis the enzyme activity did not distinctly differ from the control values. The animals with high initial content of glutathione-peroxidase in aorta were shown to be less subjected to the impairment in alimentary atherosclerosis.
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Lankin, V. Z., Gurevich, S. M., Kotelevtseva, N. V., Tikhaze, A. K., Gerasimova, E. N. (1976). Role of lipid peroxides in the pathogenesis of arteriosclerosis. Detoxication of lipid peroxides by the glutathione-peroxidase system in the aorta. Voprosy meditsinskoi khimii, 22(3), 392-395.
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