Exometabolites of some anaerobic microorganisms of human microflora

Beloborodova N.V.1 , Bairamov I.T.1, Olenin A.Yu.1, Fedotcheva N.I.2

1. Bakoulev Center for Cardiovascular Surgery RAMS
2. Institute of Theoretical and Experimental Biophysics, RAS
Section: Experimental/Clinical Study
DOI: 10.18097/pbmc20115701095      PubMed Id: 21516781
Year: 2011  Volume: 57  Issue: 1  Pages: 95-105
Some exometabolites produced by basic representatives of human anaerobic microflora were investigated, detected by gas chromatography - mass spectrometry (GC-MS). In vitro besides lactic acid Bifidobacterium and Lactobacillus generate substantial amounts of phenyllactic and p-hydroxyphenyllactic acids. Clostridium produced 2-hydroxybutyric acid and to a lesser extent lactic and phenyllactic acids. In contrast to С. perfringens, C. sporogenes generates substantial amount of phenylpropionic and p-hydroxyphenylpropionic acids and less p-hydroxyphenyllactic acid. С. perfringens produced minor amounts of 2-hydroxyglutaric acid. Bacteroids are potent producers of succinic and fumaric acids; they also contribute to production of significant portion of lactic acid. E. lentum generate lactic, phenyllactic and succinic acids and form a characteristic only for ones (from studied microorganisms) 2-hydroxyhexanic and 2-hydroxy-3-methylbutyric acids.
Download PDF:
Keywords: GS-MS, metabolites, anaerobes

Beloborodova, N. V., Bairamov, I. T., Olenin, A. Yu., Fedotcheva, N. I. (2011). Exometabolites of some anaerobic microorganisms of human microflora. Biomeditsinskaya khimiya, 57(1), 95-105.
 2020 (vol 66)
 2019 (vol 65)
 2018 (vol 64)
 2017 (vol 63)
 2016 (vol 62)
 2015 (vol 61)
 2014 (vol 60)
 2013 (vol 59)
 2012 (vol 58)
 2011 (vol 57)
 2010 (vol 56)
 2009 (vol 55)
 2008 (vol 54)
 2007 (vol 53)
 2006 (vol 52)
 2005 (vol 51)
 2004 (vol 50)
 2003 (vol 49)