Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga)

   
Nikitina S.A.1 , Khabibrakhmanova V.R.1, Sysoeva M.A.1

1. Kazan National Research Technological University, Kazan, Russia
Section: Review
DOI: 10.18097/PBMC20166204369      PubMed Id: 27562990
Year: 2016  Volume: 62  Issue: 4  Pages: 369-375
Data on the chemical composition of triterpenic and steroid compounds, isolated from the chaga mushroom grown in natural environment or in a synthetic culture have been summarized. Special attention has been paid to the biological activity of chaga mushroom extracts and these particular compounds against various cancer cell lines in vitro and in vivo. This analysis has demonstrated some common features in inhibition of growth of various cell lines by chaga mushroom components. In this context, the most active are triterpene compounds containing OH group at C-22 and a side chain unsaturated bond.
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Keywords: chaga mushroom, triterpenes, steroids, biological activity, in vivo, in vitro
Citation:

Nikitina, S. A., Khabibrakhmanova, V. R., Sysoeva, M. A. (2016). Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga). Biomeditsinskaya khimiya, 62(4), 369-375.
This paper is also available as the English translation: 10.1134/S1990750816010108
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