Voprosy meditsinskoi khimii (ISSN 0042-8809)

Incorporation of labeled amino acids into proteins of organs and tissues of rabbit after cessation of vital activity of the body and during resuscitation

   
Konikova A.S., Pogosova A.V., Nikulin V.I.
PubMed Id: 5317617
Year: 1971 vol: 17  issue:4  pages: 369-373
Abstract: Protein synthesis was assayed through incorporation of labelled amino acids (I-C14-glycine and S15-methionine) into proteins of organs and tissues of rabbit after cessation of life activity of the organism and during reanimation. It is established that after death, protein synthesis ceased in different organs and tissues not at the same time. First of all, protein synthesis stops in the spleen while in the pancreas this process persists for a longest time. Interruption of assimilatory processes after cessation of life is reversible, but restoration of the process of protein synthesis in various organs occurs not uniformly. Ambiguous restoration of precursor utilisation by organs in the process of protein biosynthesis reflects characteristics of the course of this assimilatory process in resuscitated+ animals at early stages after reanimation.
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Reference: Konikova A.S., Pogosova A.V., Nikulin V.I., Incorporation of labeled amino acids into proteins of organs and tissues of rabbit after cessation of vital activity of the body and during resuscitation, Voprosy meditsinskoi khimii, 1971, vol: 17(4), 369-373.
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