Voprosy meditsinskoi khimii (ISSN 0042-8809)

Interaction of fibrin-stabilizing factor with plasmin in vitro

Rustamova B.A., Molchanoca L.V.
PubMed Id: 4283610
Year: 1971 vol: 17  issue:4  pages: 379-382
Abstract: Investigation of interaction between fibrin-stabilizing factor and plasmin on the system of pure proteins evidenced that specific activity of fibrin-stabilizing factor falls with an increase in the optical density of TCA filtrate in the incubation medium. However fibrinolytic activity in the incubation medium increases. This is manifested by an increase of the lysine zone at the fibrin plates and by an acceleration of lysis of the standard clot. The action of plasmin on fibrinogen and that of trypsin on fibrin-stabilizing factor does not lead to an appearance of such an activity.
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Reference: Rustamova B.A., Molchanoca L.V., Interaction of fibrin-stabilizing factor with plasmin in vitro, Voprosy meditsinskoi khimii, 1971, vol: 17(4), 379-382.