Voprosy meditsinskoi khimii (ISSN 0042-8809)

Role of bile acids and phospholipids in the stabilization of cholesterol in the gallbladder bile

   
Fedorova V.M.
PubMed Id: 5317619
Year: 1971 vol: 17  issue:4  pages: 382-384
Abstract: A removal of bile acids from the bile by gel-filtration results in a decrease of coagulation threefold of the cholesterol micelle. During enzymatic cleavage of phospholipids in the whole bile, cholesterol is retained in the solution. Under the same treatment of a fraction isolated from the dog bile employing filtration through Sephadex G-75 and devoid of bile acids, cholesterol completely precipitated. The data obtained indicate an important role of fatty acids in the stabilization of cholesterol in the bile, phospholipids play a less role in this process.
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Reference: Fedorova V.M., Role of bile acids and phospholipids in the stabilization of cholesterol in the gallbladder bile, Voprosy meditsinskoi khimii, 1971, vol: 17(4), 382-384.
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