Voprosy meditsinskoi khimii (ISSN 0042-8809)

Carbohydrate metabolism during poisoning with the cholinesterase inhibitor O-ethyl-S-hexylmethylthiophosphonate

   
Rozengart V.I., Chetverikova E.K., Mozgovaia I.A.
PubMed Id: 5317625
Year: 1971 vol: 17  issue:4  pages: 403-407
Abstract: It is established that a decrease in glycogen content in liver begins at the early stages of intoxication with LG-63 and progresses with development of intoxication phenomena. Sugar content in liver and blood augments in parallel with decreasing content of glycogen in liver; concentration of ketone bodies and content of bisulfite-binding substances and pyruvic acid in liver also increase. In skeletal muscles, glycogen content was practically without changes; content of sugar, bisulfite-binding substances and pyruvic acid decreased while level of ketone bodies increased. In brain, utilization of ketone bodies decreased and in myocardium, increased.
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Reference: Rozengart V.I., Chetverikova E.K., Mozgovaia I.A., Carbohydrate metabolism during poisoning with the cholinesterase inhibitor O-ethyl-S-hexylmethylthiophosphonate, Voprosy meditsinskoi khimii, 1971, vol: 17(4), 403-407.
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