Voprosy meditsinskoi khimii (ISSN 0042-8809)

Change in the protein spectrum of the erythrocytic membranes in certain anemias

   
Kamyshentsev M.V., Blinov M.N., Abdulkadyrova A.S.
PubMed Id: 1119119
Year: 1975 vol: 21  issue:1  pages: 95-98
Abstract: Proteins of human erythrocyte membranes were studied in normal state and in different anaemias. After solubilization of cell 'shadows' in phenol-urea-acetic acid-water system in membranes there were found, by means of polyacrylamide gel disc electrophoresis, 20 protein fractions with molecular weight from 48000 to 225000; seven of them glycoproteins. In 9 cases out of 36 a complete or partial disappearance of a glycoprotein component with molecular weight of 170000 was observed in erythrocyte membranes from patients with inherited spherocytosis and Markiafava--Mikely disease.
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Reference: Kamyshentsev M.V., Blinov M.N., Abdulkadyrova A.S., Change in the protein spectrum of the erythrocytic membranes in certain anemias, Voprosy meditsinskoi khimii, 1975, vol: 21(1), 95-98.
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