Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of a malic acid load on the blood and urine content in animals of the products of a malate dehydrogenase reaction and the correlation of reduced and oxidized forms of ascorbic acid

   
Romanovich E.A., Basieva F.I.
PubMed Id: 1138497
Year: 1975 vol: 21  issue:2  pages: 131-133
Abstract: Addition of 150 mg of malic acid per a day to food of rabbits caused an increase in content of reduced ascorbic acid and pyruvic acid in blood; at the same time the content of oxydized forms of ascorbic acid was decreased. Similar alterations were observed in urine of guinea-pigs, which received 100 mg of malic acid per a day. The data obtained suggest that under these conditions the increased reduction, of ascorbic acid was due to increased formation of NADP with H2 in the course of reaction, catalyzed by malate dehydrogenase.
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Reference: Romanovich E.A., Basieva F.I., Effect of a malic acid load on the blood and urine content in animals of the products of a malate dehydrogenase reaction and the correlation of reduced and oxidized forms of ascorbic acid, Voprosy meditsinskoi khimii, 1975, vol: 21(2), 131-133.
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