Voprosy meditsinskoi khimii (ISSN 0042-8809)

Serotonin metabolism in acute renal ischemia in rabbits

Ermolaev M.V., Khovanskaia T.P.
PubMed Id: 1138500
Year: 1975 vol: 21  issue:2  pages: 147-150
Abstract: In tissue of ischemic kidney of rabbits a 5-hydroxytryptophan decarboxylase activity was decreased at first 15 min of ischemia; in contralateral kidney it was slightly increased. Then, within all the studied periods (24 hrs), activity of the enzyme was gradually decreased in both kidneys. The monoamine oxidase activity (substrates serotonin and p-nitrophenyl ethylamine) changed alternatively in early periods of ischemia; it tended to increase, especially in contralateral kidney, within 3 hrs after constriction of kidney artery.
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Reference: Ermolaev M.V., Khovanskaia T.P., Serotonin metabolism in acute renal ischemia in rabbits, Voprosy meditsinskoi khimii, 1975, vol: 21(2), 147-150.