Voprosy meditsinskoi khimii (ISSN 0042-8809)

Study of proteins of rat skeletal muscles in experimental rickets

Nikolaeva E.N., Fonarev M.I.
PubMed Id: 128894
Year: 1975 vol: 21  issue:3  pages: 249-254
Abstract: In dynamics of experimental rickets proteins of rat sceletal muscles were studied after and before physical exercises. Occurrence of rickets was estimated by following concentration of inorganic phosphorus and calcium in blood and by X-ray examination of knee joint. An increase in total amount of sarcoplasmic proteins was observed within the first week of development of the disease. After physical exercices the effect was noticed also within the second week of the development of rickets. Content of fractions of the sarcoplasmic proteins was similar in all animals and within all the periods studied. Within four weeks content of myofibrillar proteins was decreased in rickety rats, which were not subjected to physical exercices. In rats of the both experimental groups the ATPase activity of actomyosin was not distinctly altered within all the periods studied.
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Reference: Nikolaeva E.N., Fonarev M.I., Study of proteins of rat skeletal muscles in experimental rickets, Voprosy meditsinskoi khimii, 1975, vol: 21(3), 249-254.