Voprosy meditsinskoi khimii (ISSN 0042-8809)

Transketolase activity in rabbit myocardium and erythrocytes in health and in allergic heart diseases

   
Grosdova M.D., Astakhova T.A.
PubMed Id: 1216755
Year: 1975 vol: 21  issue:4  pages: 363-366
Abstract: Transketolase activity was determined in myocardium and erythrocytes of rabbits by following formation of D-sedoheptuloso-7-phosphate (S-7-P), when the convertion of the substance was blocked in a transaldolase reaction by addition of 3-phosphoglycerol aldehyde dehydrogenase. In the transaldolase reaction consumption of the S-7-P did not exceed 5% of the amount of this compound, produced in the transketolase reaction. In allergic impairment alterations in the transketolase activity occurred simultaneously with a change in the level of plastic metabolism in myocardium. The transketolase activity was decreased when destructive processes were stimulated. But the transketolase activity was distinctly increased under the conditions, characterized by activation of protein biosynthesis.
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Reference: Grosdova M.D., Astakhova T.A., Transketolase activity in rabbit myocardium and erythrocytes in health and in allergic heart diseases, Voprosy meditsinskoi khimii, 1975, vol: 21(4), 363-366.
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