Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of acetycholine on the Ca2+ transport system in sarcoplasmic reticulum of frog skeletal muscle

   
Esyrev O.V., Uspanova Z.K.
PubMed Id: 1035991
Year: 1976 vol: 22  issue:1  pages: 21-25
Abstract: In fragments of sarcoplasmic reticulum of the frog abdominal straight muscle the functional properties of Ca2+ transport and effect of acetycholine on those properties were studied. The rate of Ca2+ accumulation was decreased due to stimulation by acetylcholine the Ca2+ out-flow from the reticular vesicles. The ratio Ca2+/ATP decreased and the Ca2+-ATPase activity was increased. The Ki vlaue for the inhibition by acetylcholine of Ca2+ absorption was 60micronM. Effect of acetylcholine on the Ca2+ transport depended on the temperature of medium.
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Reference: Esyrev O.V., Uspanova Z.K., Effect of acetycholine on the Ca2+ transport system in sarcoplasmic reticulum of frog skeletal muscle, Voprosy meditsinskoi khimii, 1976, vol: 22(1), 21-25.
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