Voprosy meditsinskoi khimii (ISSN 0042-8809)

Activity of lactate dehydrogenase and its isoenzymes in the thrombocytes in different forms of cerebral circulatory disorder

   
Khmara N.F., Trukhan A.S.
PubMed Id: 1030886
Year: 1976 vol: 22  issue:2  pages: 183-187
Abstract: In thrombocytes of patients with ischemic and hemorrhagic insult a transformation in the isozyme spectrum of lactate dehydrogenase was observed without an alteration in the reaction rate. In this case LDH3 was decreased and LDH1 and LDH4 were increased. The correlation was not found between the type of insult and the character of the isozyme spectrum. The alterations were considered as an adaptive mechanism and the reflected the extent of immediate or intermediate effect of ischemia on thrombocytes.
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Reference: Khmara N.F., Trukhan A.S., Activity of lactate dehydrogenase and its isoenzymes in the thrombocytes in different forms of cerebral circulatory disorder, Voprosy meditsinskoi khimii, 1976, vol: 22(2), 183-187.
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