Voprosy meditsinskoi khimii (ISSN 0042-8809)

HCO3- -stimulated ATPase of rat kidneys

Ivashchenko A.T., Zhubanova A.A.
PubMed Id: 193292
Year: 1976 vol: 22  issue:2  pages: 258-260
Abstract: In homogenate and mitochondria of cortex and medulla of rat kidney a stimulating effect of different concentrations of bicarbonate on the ATPase activity was studied. By the rate of inhibition of Mg2+-ATPase and HCO3-ATPase, thiocyanate, perchlorate and azide were distributed as follows: N3 greater than CNS greater than ClO4. Thiocyanate inhibited non-competitively the HCO3-stimulated ATPase activity. The similarity was observed between HCO3-stimulated ATPase from rat kidney and bicarbonate-stimulated ATPase from other cells.
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Reference: Ivashchenko A.T., Zhubanova A.A., HCO3- -stimulated ATPase of rat kidneys, Voprosy meditsinskoi khimii, 1976, vol: 22(2), 258-260.