Voprosy meditsinskoi khimii (ISSN 0042-8809)

Methylmalonic acid excretion in experimental B2-avitaminosis in rats

   
Kastrikina L.N., Churdaleva E.V., Spirichev V.B.
PubMed Id: 16395
Year: 1976 vol: 22  issue:2  pages: 269-274
Abstract: Providing of rats with a diet, deficient in vitamin B2 within 2 and 5 weeks, was not shown to be accompanied by an increase in excretion of methylmalonic acid. In the animals some tendency to the increased excretion of methylmalonic acid was observed within 8 weeks of the diet. The data obtained suggest that the test for excretion of methylmalonic acid was the highly specific as a pattern of supply with vitamin B12. The possible role of vitamin B2 and flavoproteins in biosynthesis of coenzyme forms of vitamin B12 is discussed.
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Reference: Kastrikina L.N., Churdaleva E.V., Spirichev V.B., Methylmalonic acid excretion in experimental B2-avitaminosis in rats, Voprosy meditsinskoi khimii, 1976, vol: 22(2), 269-274.
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