Voprosy meditsinskoi khimii (ISSN 0042-8809)

Protein biosynthesis of the xenogeneic heart during perfusion with the aid of a donor

   
Korotkina R.N., Nikulin V.I.
PubMed Id: 800302
Year: 1976 vol: 22  issue:4  pages: 465-469
Abstract: Biosynthesis of sarcoplasmic and contractile proteins was studied in cat heart, extracorporeally connected to the rabbit circulation. Biosynthesis of sarcoplasmic proteins was inhibited by 34-40% in ventriculus dexter of the perfused xenogenic heart. Heteroperfusion caused an increased incorporation of 35S-methionine into total proteins of the right auricle and of the interventricular septa and also into contractile proteins of both myocardium ventricles of rabbit-donor. The heteroperfusion did not affect the penetration of the labelled amino acid into various parts of perfused and donor hearts.
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Reference: Korotkina R.N., Nikulin V.I., Protein biosynthesis of the xenogeneic heart during perfusion with the aid of a donor, Voprosy meditsinskoi khimii, 1976, vol: 22(4), 465-469.
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