Voprosy meditsinskoi khimii (ISSN 0042-8809)

Electrophoretic study of liver histones in the postnatal ontogeny of white rats: the effect of testosterone propionate and gonadectomy

   
Klimenko A.I., Khints R.R.
PubMed Id: 1027242
Year: 1976 vol: 22  issue:4  pages: 547-551
Abstract: By means of polyacrylamide gel disc electrophoresis heterogeneity, electrophoretic mobility and relative content of different fractions of histones in nuclei of liver cells were studied in gonadectomized Wistar rats and in castrated in intact animals, administered with testosteone propionate. In all the experiments a significant conservatism of histone proteins was found in postnatal development. In animals, treated with the endocrine preparations, the age peculiarities were shown to reflect the quanitative proportion of different histone fractions.
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Reference: Klimenko A.I., Khints R.R., Electrophoretic study of liver histones in the postnatal ontogeny of white rats: the effect of testosterone propionate and gonadectomy, Voprosy meditsinskoi khimii, 1976, vol: 22(4), 547-551.
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