Voprosy meditsinskoi khimii (ISSN 0042-8809)

Possible change in the substrate specificity of the monoamine oxidase of rat brain and liver mitochondria in hyperoxia

   
Goroshinskaia I.A., Bronovitskaia Z.G.
PubMed Id: 1027243
Year: 1976 vol: 22  issue:4  pages: 558-562
Abstract: Maintenance of animals in conditions of increased oxygen pressure at 4 atm within 1 h caused a decrease in activity of monoamine oxidase from rat brain mitochondria and liver tissue; at the same time, deamination of putrescine and AMP was increased. Deamination of glucosamine was also observed in brain mitochondria. The qualitative alterations in the monoamine oxidase activity were more distinct in brain than in liver tissue. The enzymatic activity was partially restored by addition of ascorbic acid to the suspension of mitchondria.
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Reference: Goroshinskaia I.A., Bronovitskaia Z.G., Possible change in the substrate specificity of the monoamine oxidase of rat brain and liver mitochondria in hyperoxia, Voprosy meditsinskoi khimii, 1976, vol: 22(4), 558-562.
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