Voprosy meditsinskoi khimii (ISSN 0042-8809)

Tissue metabolism of thyroid hormones in cirrhosis of the liver

   
Mirakhmedov M.M., Turakulov I.Kh.
PubMed Id: 1014477
Year: 1976 vol: 22  issue:5  pages: 655-659
Abstract: Content and ratio of products of iodothyronine tissue metabolism was studied in liver tissue of rats in normal state and in hepatocirrhosis after administration of 125I-thyroxin. The distinct decrease was observed in accumulation, deiodination and conjugation of thyroxin; the hormone was also converted into triiodothyronine in cirrhotically altered liver tissue. The importance of liver tissue in maintenance of hormonal homeostasis and biological activation of thyroid hormones is discussed.
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Reference: Mirakhmedov M.M., Turakulov I.Kh., Tissue metabolism of thyroid hormones in cirrhosis of the liver, Voprosy meditsinskoi khimii, 1976, vol: 22(5), 655-659.
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