Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of insulin of acetylation of histones and non-histone proteins in the cell nuclei of the liver of albine rats of different age

   
Klimenko A.I., Simirenko L.L.
PubMed Id: 1027251
Year: 1976 vol: 22  issue:6  pages: 795-798
Abstract: After administration of insulin acetylation of histones and acid proteins in liver cell nuclei was decreased within 30 min; it increased gradually within 120 min and there was no difference as compared with control within 360 min in young animals. Incorporation of acetate label into proteins was inhibited within 90 min after the hormone loading in old animals and it did not differ from control within 120 min. Under these conditions acetylation of globulin proteins was decreased within 30 min; it approached the control level within 60 min after which it did not distinctly alter ad compared with the control.
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Reference: Klimenko A.I., Simirenko L.L., Effect of insulin of acetylation of histones and non-histone proteins in the cell nuclei of the liver of albine rats of different age, Voprosy meditsinskoi khimii, 1976, vol: 22(6), 795-798.
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