Voprosy meditsinskoi khimii (ISSN 0042-8809)

Activity of protein-synthesizing system and RNA synthesis in the liver and spleen of rats in stress caused by burns

   
Abakumova O.Yu., Kutsenko N.G.
PubMed Id: 1027255
Year: 1976 vol: 22  issue:6  pages: 826-830
Abstract: Period of decreased protein synthesis was observed in rats within first hours, after burns but later on the synthesis was distinctly increased in liver and spleen tissues. This increase was apparently due to induction of RNA synthesis as actinomycin D removed the effect of burns on the protein synthesis. Immediately after the burns incorporation of 14C-orotic acid into rapidly-lebelling RNA of rat liver tissue was increased; the increased RNA synthesis was observed and at the 3-rd day after burns.
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Reference: Abakumova O.Yu., Kutsenko N.G., Activity of protein-synthesizing system and RNA synthesis in the liver and spleen of rats in stress caused by burns, Voprosy meditsinskoi khimii, 1976, vol: 22(6), 826-830.
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