Voprosy meditsinskoi khimii (ISSN 0042-8809)

Glucose-6-phosphate dehydrogenase in rat liver and myocardium following toxic doses of noradrenaline

   
Shanygina K.I., Novikova N.A.
PubMed Id: 888400
Year: 1977 vol: 23  issue:3  pages: 358-360
Abstract: Administration of toxic doses of noradrenaline into rats led to exhaustion of noradrenaline reserves in liver and heart tissues with the simultaneous increase in the activity of glucose-6-phosphate dehydrogenase in the tissues. Actinomycin D, administered together with noradrenaline, completely prevented the elevation of the G6PD activity in the tissues studied. The data obtained suggest that sympathetic nervous system and its mediator are responsible for regulation of the rate of enzymatic protein synthesis in tissues.
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Reference: Shanygina K.I., Novikova N.A., Glucose-6-phosphate dehydrogenase in rat liver and myocardium following toxic doses of noradrenaline, Voprosy meditsinskoi khimii, 1977, vol: 23(3), 358-360.
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