Voprosy meditsinskoi khimii (ISSN 0042-8809)

Age and changes in the activity of several energy metabolism enzymes in the rabbit aorta

   
Mikhaĭlova I.A., Nadirova T.Ya.
PubMed Id: 200002
Year: 1977 vol: 23  issue:4  pages: 463-468
Abstract: Age alterations in the activity of several key enzymes of glucose oxidative breakdown (hexokinase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and cytochrome c oxidase) were studied in extracts from rabbit aorta. The hexokinase activity was measured also in mitochondrial fraction. The activity of all the enzymes studied in rabbit aorta (calculated either per 1 g of the tissue or per 1 mg of proteins) was the highest at the age from 1-2 weeks to 1 month. The minimal activity was observed in adult animals, which were 1-2 years old, In aorta of 3,5-4 years old rabbits an increase (per 1 g of the tissue) in the activity of the enzymes was observed.
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Reference: Mikhaĭlova I.A., Nadirova T.Ya., Age and changes in the activity of several energy metabolism enzymes in the rabbit aorta, Voprosy meditsinskoi khimii, 1977, vol: 23(4), 463-468.
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