Voprosy meditsinskoi khimii (ISSN 0042-8809)

Fucoglycoproteins in the biological fluids of relatives of peptic ulcer patients

   
Rabinovich P.D., Domracheva N.I.
PubMed Id: 919371
Year: 1977 vol: 23  issue:4  pages: 478-482
Abstract: Comparative studies of 89 people originating from healthy families and of 103 relatives of patients with ulcerous disease revealed in the latter group more frequent occurrence of the O (I) group of blood, nonsecretory status as evidenced by ABH or secretion of group antigen "H", an increase in content of high molecular fucoglycoproteins in blood serum and increased urinary excretion of fucoglycopeptides. The data obtained suggest that impairment of secretion of fucoglycoproteins in ulcerous disease is hereditary determined; the impairment may faster development of chronic ulcer in the gastroduodenum due to weakening of the barrier function of the system
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Reference: Rabinovich P.D., Domracheva N.I., Fucoglycoproteins in the biological fluids of relatives of peptic ulcer patients, Voprosy meditsinskoi khimii, 1977, vol: 23(4), 478-482.
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