Voprosy meditsinskoi khimii (ISSN 0042-8809)

Catecholamine storage in schizophrenia

Baru A.M., Mys'ko G.N.
PubMed Id: 919379
Year: 1977 vol: 23  issue:4  pages: 550-554
Abstract: After administration of isadrine excretion of noradrenaline was increased in schizophrenic patients with symptoms of depression or anxiety. This phenomenon was not observed in healthy persons and in patients with circular depression. Data on liberation of noradrenaline by other amines in schizophrenia and displacement of noradrenaline in schizophrenia by isadrine, which does not accumulate in normal storage sites, suggest that storage of noradrenaline is impaired in schizophrenia.
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Reference: Baru A.M., Mys'ko G.N., Catecholamine storage in schizophrenia, Voprosy meditsinskoi khimii, 1977, vol: 23(4), 550-554.