Voprosy meditsinskoi khimii (ISSN 0042-8809)

Tyrosine-alpha-ketoglutarate transaminase activity in the rat liver after partial hepatectomy and CCl4 poisoning

   
Iakobson G.S., Sorokin A.S., Gizatulin Z.Ya., Shorin I.P.
PubMed Id: 22956
Year: 1977 vol: 23  issue:5  pages: 701-703
Abstract: Acitivity of tyrosine-alpha-ketoglutarate transaminase and induction of the enzyme by hydro cortisone were studied in rat liver tissue after partial hepatectomy and intoxication with CCl4 Administration of the hormone increased the enzymatic activity within 72 hrs after treatment with CCl4 but did not affect its value within 8 and 24 hrs. Activation of the enzyme by hydrocortisone correlated with the increased enzymatic activity observed within 20 hrs after partial hepatectomy. Possible mechanisms for activation of the enzyme, caused by endo- and exogenous factors, are discussed.
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Reference: Iakobson G.S., Sorokin A.S., Gizatulin Z.Ya., Shorin I.P., Tyrosine-alpha-ketoglutarate transaminase activity in the rat liver after partial hepatectomy and CCl4 poisoning, Voprosy meditsinskoi khimii, 1977, vol: 23(5), 701-703.
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