Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of hexenal and thiopental anesthesia on energy metabolism in different brain areas

   
Batrak G.E., Nerush P.A.
PubMed Id: 595482
Year: 1977 vol: 23  issue:6  pages: 745-748
Abstract: Respiration and oxidative phosphorylation were studied in dog mitochondria of visua and acoustic areas of brain cortex as well as of medial thalamus after hexenal and thiopental narcosis. The distinct increase in the respiratory activity, which was not accompanied by phosphate esterification, was observed in mitochondria of medial thalamus as compared with the organelles of brain cortex from visual and acoustic areas. The phenomenon was responsible for uncoupling of respiration and phosphorylation processes.
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Reference: Batrak G.E., Nerush P.A., Effect of hexenal and thiopental anesthesia on energy metabolism in different brain areas, Voprosy meditsinskoi khimii, 1977, vol: 23(6), 745-748.
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