Voprosy meditsinskoi khimii (ISSN 0042-8809)

Phospholipid composition of high density lipoproteins in hyperalphalipoproteinemia

   
Torkhovskaia T.I., Koldaeva A.P., Kurchatova S.A., Titov V.N., Gerasimova E.N.
PubMed Id: 202089
Year: 1977 vol: 23  issue:6  pages: 768-773
Abstract: Content of lecithin as related to the total content of phospholipids was increased in alpha-lipoproteins of healthy men with hyper-alpha-lipoproteinemia (concentration of cholesterol exceeded 72 mg% in the lipoproteins). The alpha-lipoproteins accumulated considerably more free cholesterol than its esters; this caused a decrease in the molar ration "phospholipids/free cholesterol". The surface of phospholipid-cholesterol monolayer of alpha-lipoproteins is apparently responsible for retaining of increased amounts of cholesterol in the complex as well as for participation of these structures in enzymatic reactions in blood serum.
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Reference: Torkhovskaia T.I., Koldaeva A.P., Kurchatova S.A., Titov V.N., Gerasimova E.N., Phospholipid composition of high density lipoproteins in hyperalphalipoproteinemia, Voprosy meditsinskoi khimii, 1977, vol: 23(6), 768-773.
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