Voprosy meditsinskoi khimii (ISSN 0042-8809)

Nature of the lipoprotein antigen responsible for the development of resistance to experimental atherosclerosis following its use in immunization of newborn rabbits

   
Klimov A.N., Loviagina T.N., Nagornev V.A., Zubzhitsky Yu.N., Petrova-Maslakova L.G., Bankovskaya E.B., Magracheva E.Ya., Olejnik I.A.
PubMed Id: 208295
Year: 1978 vol: 24  issue:1  pages: 131-136
Abstract: In order to develop a tolerance to experimental atherosclerosis newborn rabbits were immunized with various fractions of atherogenic lipoproteins (lipoproteins of low density, lipoproteins of very low density and total fraction of these lipoproteins), isolated from blood serum of adult rabbits with experimental hypercholesterolemia. The tolerance to atherosclerosis proved to be achieved in immunization with lipoproteins of very low density. The lesser effect was observed using the total fraction of lipoproteins. The tolerance was not developed in immunization with lipoproteins of low density.
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Reference: Klimov A.N., Loviagina T.N., Nagornev V.A., Zubzhitsky Yu.N., Petrova-Maslakova L.G., Bankovskaya E.B., Magracheva E.Ya., Olejnik I.A., Nature of the lipoprotein antigen responsible for the development of resistance to experimental atherosclerosis following its use in immunization of newborn rabbits, Voprosy meditsinskoi khimii, 1978, vol: 24(1), 131-136.
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