Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of the prolonged administration of the atherogenic fractions of lipoproteins on the blood and myocardial lipid picture in rabbits

   
Kalinkin M.N., Bel'chenko D.I.
PubMed Id: 208285
Year: 1978 vol: 24  issue:2  pages: 147-151
Abstract: Homologous total fraction of pre-beta and beta-lipoproteins, isolated from intact animal blood and administered intravenously into rabbits within 1.5-2 months, caused distinct alterations in lipid spectra of rabbit-recipient blood serum. The phenomenon was manifested as an increase in concentration of all the lipid components in blood plasma, elevation in content of pre-beta and beta-lipoproteins in blood and decrease in content of alpha-lipoproteins. The alterations were apparently related not only to excessive administration of atherogenic lipoproteins but to impairments in lipid metabolism, similar to lipoproteinemia, reproduced in other experiments.
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Reference: Kalinkin M.N., Bel'chenko D.I., Effect of the prolonged administration of the atherogenic fractions of lipoproteins on the blood and myocardial lipid picture in rabbits, Voprosy meditsinskoi khimii, 1978, vol: 24(2), 147-151.
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