Voprosy meditsinskoi khimii (ISSN 0042-8809)

Intensity of the metabolism of separate brain phospholipid fractions in hyperphenylalaninemia

   
Zuber V.L.
PubMed Id: 664439
Year: 1978 vol: 24  issue:2  pages: 163-166
Abstract: Effect of acute and chronic forms of hyperphenylalaninemia on intensity of metabolism and content of some phospholipid fractions was studied in brain of growing rats. Acute form of hyperphenylalaninemia caused a decrease in metabolic activity of phospholipids but did not affect their content. In chronic hyperphenylalaninemia more distinct alterations in brain phospholipids metabolism were manifested as a decrease in their content and in their metabolic intensity. The data obtained suggest that brain demyelination developed in chronic hyperphenylalaninemia.
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Reference: Zuber V.L., Intensity of the metabolism of separate brain phospholipid fractions in hyperphenylalaninemia, Voprosy meditsinskoi khimii, 1978, vol: 24(2), 163-166.
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