Voprosy meditsinskoi khimii (ISSN 0042-8809)

Distribution and properties of the alkaline phosphatase in the human gastric mucosa in peptic ulcer

   
Ivanov G.G.
PubMed Id: 664446
Year: 1978 vol: 24  issue:2  pages: 206-210
Abstract: In duodenal ulcer alkaline phosphatase activity was the highest in mucosa of pyloric region of curvature ventriculi minor and it decreased distinctly in the tissues removed from pylorus. In cases of gastric ulcer, the enzymatic activity was high throughout the curvatura ventriculi minor reaching the maximal value at the ulcerous zone. Alkaline phosphatase from gastric mucosa resembled the enzyme from intestine in its inhibition patterns with 1-phenylalanine and in inactivation properties at 56 degrees within 15 min; but, as distinct from the latter, the enzyme was more stable at 65 degrees within 5 min, maintaining 50% of the initial activity.
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Reference: Ivanov G.G., Distribution and properties of the alkaline phosphatase in the human gastric mucosa in peptic ulcer, Voprosy meditsinskoi khimii, 1978, vol: 24(2), 206-210.
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