Voprosy meditsinskoi khimii (ISSN 0042-8809)

Relative content of the alpha-, beta- and gamma-chains of the soluble collagen fractions from the bone tissue of rats with a varying supply of vitamin D

   
Isaeva V.A., Spirichev V.B.
PubMed Id: 664454
Year: 1978 vol: 24  issue:2  pages: 270-274
Abstract: Insufficiency of vitamin D caused a decrease in content of salt- and acid soluble collagen fractions with simultaneous increase of insoluble its fraction in epiphyses of rat tubular bones. At the same time relative content of monomeric alpha-chains was decreased but content of dimeric (beta-chains) and trimeric (gamma-chains) subunits was increased in both collagen fractions. These data are in good agreement with assumption on the increased growth of bone collagen under insufficiency of vitamin D.
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Reference: Isaeva V.A., Spirichev V.B., Relative content of the alpha-, beta- and gamma-chains of the soluble collagen fractions from the bone tissue of rats with a varying supply of vitamin D, Voprosy meditsinskoi khimii, 1978, vol: 24(2), 270-274.
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