Voprosy meditsinskoi khimii (ISSN 0042-8809)

Therapeutic effect of myelin basic protein and synthetic encephalitogenic peptide in guinea pigs with experimental allergic encephalomyelitis

   
Belik I.V., Terletskaia I.T., Kozulina E.P., Syrovatskaia L.P., Gershkovich A.A.
PubMed Id: 78577
Year: 1978 vol: 24  issue:3  pages: 372-377
Abstract: Effect of antigenic factors of experimental allergic encephalomyelitis (alkaline protein of myelin and synthetic encephalitogenic peptide) was studied in guinea pigs with distinct manifestations of the experimental allergic encephalomyelitis. The animals recovered after prolonged administration of alkaline protein of myelin within 14 days, if they were sensibilized either by bovine alkaline protein of myelin or by synthetic encephalitogenic peptide. Synthetic encephalitogenic peptide was only effective in treatment of the disease caused by the peptide.
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Reference: Belik I.V., Terletskaia I.T., Kozulina E.P., Syrovatskaia L.P., Gershkovich A.A., Therapeutic effect of myelin basic protein and synthetic encephalitogenic peptide in guinea pigs with experimental allergic encephalomyelitis, Voprosy meditsinskoi khimii, 1978, vol: 24(3), 372-377.
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