Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of turkesterone and nerobol on the activity of the protein synthesizing system of mouse liver

   
Syrov V.N., Kurmukov A.G., Sakhibov A.D.
PubMed Id: 685188
Year: 1978 vol: 24  issue:4  pages: 456-460
Abstract: Protein biosynthesis was stimulated in liver tissue in vivo and in vitro after administration into mice of either phytoecdizone of turkesterone (0.5 mg/100 g) or of anabolic steroid compound nerobole (1 mg/100 g). Stimulation of protein biosynthesis was due to an increase in functional activity of polyribosomes and to elevation in the synthesis of protein molecules. Actinomycin D, which inhibited the stimulation of protein biosynthesis in liver tissue of mice treated with nerobole, did not affect the phenomenon in mice treated with turkesterone.
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Reference: Syrov V.N., Kurmukov A.G., Sakhibov A.D., Effect of turkesterone and nerobol on the activity of the protein synthesizing system of mouse liver, Voprosy meditsinskoi khimii, 1978, vol: 24(4), 456-460.
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