Voprosy meditsinskoi khimii (ISSN 0042-8809)

Detection of autoimmune lipoprotein--antibody complex in human plasma and aortic wall

   
Klimov A.N., Denisenko A.D., Zubzhitskiĭ I.N., Gerchikova E.A.
PubMed Id: 210589
Year: 1978 vol: 24  issue:4  pages: 539-543
Abstract: An immune complex of lipoprotein-antibody was found in human blood plasma and in tissue liquid of aorta, impaired by atherosclerosis. In the majority of cases the antigen component of the immune complex was lipoprotein of very low density. After dissociation of the complex at acid pH, immunoglobulin G was isolated, which was identified by double immunodiffusion in agar gel; the immunoglobulin reacted in RBS both with autological and, in some cases, with isological lipoproteins.
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Reference: Klimov A.N., Denisenko A.D., Zubzhitskiĭ I.N., Gerchikova E.A., Detection of autoimmune lipoprotein--antibody complex in human plasma and aortic wall, Voprosy meditsinskoi khimii, 1978, vol: 24(4), 539-543.
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