Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of biogenic amines on phosphorolysis and gamma-amylolysis of glycogen in the cardiac muscle of rats under anesthesia

   
Roze L.V., Rozenfel'd E.L.
PubMed Id: 706262
Year: 1978 vol: 24  issue:5  pages: 690-694
Abstract: Adrenaline, poradrenaline, serotonin, triptamine and 3-hydroxytyramine activated glycogen phosphorolysis in heart of nonanesthetized rats due to increase in the phosphorylase A activity. Anesthesia with nembutal and ether prevented the stimulating effect of biogenic amines (excluding serotonin) on phosphorolysis. Adrenaline, administered into animals anesthetized with nembutal, inhibited the glycogen phosphorolysis. Noradrenaline caused a decrease in gamma-amylolysis of glycogen in anesthetized and untreated rats. The inhibitory effect of adrenaline on glycogen gamma-amylolysis occurred in rat heart muscle only under the conditions of anesthesia.
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Reference: Roze L.V., Rozenfel'd E.L., Effect of biogenic amines on phosphorolysis and gamma-amylolysis of glycogen in the cardiac muscle of rats under anesthesia, Voprosy meditsinskoi khimii, 1978, vol: 24(5), 690-694.
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