Voprosy meditsinskoi khimii (ISSN 0042-8809)

Serum antiprotease activity following parenteral administration of proteolytic enzymes, histamine and acetylcholine

   
Protsenko V.A., Bogadel'nikov I.V., Spitsyn I.F.
PubMed Id: 734973
Year: 1978 vol: 24  issue:6  pages: 736-740
Abstract: State of tryptic and antienzymatic activities of rabbit blood serum was studied after parenteral administration of trypsin, chymotrypsin, histamine, acetylcholine and kallikrein. Treatment with chymotrypsine led to the most favorable alterations in animals as compared with trypsin and kallikrein effects. Activity of trypsin was increased and the antienzymatic activity was decreased in blood serum after administration of histamine and acetylcholine. This suggests that antiprotease drugs may be used in therapy of diseases, accompanied by increase in content of histamine and acetylcholine.
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Reference: Protsenko V.A., Bogadel'nikov I.V., Spitsyn I.F., Serum antiprotease activity following parenteral administration of proteolytic enzymes, histamine and acetylcholine, Voprosy meditsinskoi khimii, 1978, vol: 24(6), 736-740.
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