Voprosy meditsinskoi khimii (ISSN 0042-8809)

Functioning of rat liver mitochondria in hepatitis

Almatov K.T., Rakhimov M.M.
PubMed Id: 216141
Year: 1978 vol: 24  issue:6  pages: 740-747
Abstract: Parameters of oxidative phosphorylation, the rate of respiration in various metabolic conditions as well as an activity and stability of mitochondrial polyenzyme systems were altered in rats with experimental hepatitis, treated with CCl4. Proteins and phospholipids from mitochondrial membranes proved to be more susceptible to the effect of trypsin and phospholipase D. Kinetics of cytochrome C desorption from membranes and mitochondria demonstrated that capacity of these membranes to confine the exogenous proteins was altered in hepatitis.
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Reference: Almatov K.T., Rakhimov M.M., Functioning of rat liver mitochondria in hepatitis, Voprosy meditsinskoi khimii, 1978, vol: 24(6), 740-747.