Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of precipitating antibodies to pancreatic kallikrein on arginine esterase contact activation in human and rabbit blood

   
Karpitskiĭ V.V., Guz S.Ya.
PubMed Id: 452486
Year: 1979 vol: 25  issue:3  pages: 242-245
Abstract: Effect of precipitating antibodies against pig pancreatic kallikrein on the BAEE-esterase activity was studied in human blood plasma and in rabbit blood serum, activated by kaolin. An inhibitory effect of the antibodies on the increased BAEE-esterase activity was observed within the first minute of incubation after treatment with kaolin. The inhibition of the BAEE-esterase activity constituted 65.1% in human blood plasma and 40.9% in rabbit serum. Possible mechanism is discussed on the inhibition of contact activation of arginine esterase in human and rabbit blood by antibodies against pancreatic kallikrein.
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Reference: Karpitskiĭ V.V., Guz S.Ya., Effect of precipitating antibodies to pancreatic kallikrein on arginine esterase contact activation in human and rabbit blood, Voprosy meditsinskoi khimii, 1979, vol: 25(3), 242-245.
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