Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of anabolic steroid hormones on protein and lipid metabolic indices in thermal injury

   
Bogdarin I.A.
PubMed Id: 452491
Year: 1979 vol: 25  issue:3  pages: 274-278
Abstract: Burns of 20% of rat skin caused a decrease in content of albumins and gamma-globulins in blood and simultaneous increase in content of alpha 1- and alpha 2-globulins. Content C17 : 1 and C19 : 1 monoenoic fatty acids was decreased in blood and liver tissue of the rats with burns. These patterns were normalized after administration into the animals of synthetic anabolic steroid nerobolyl at a dose 5 mg/kg. Burning castrated male rats led to a decrease in concentration of albumins, alpha 1- and alpha 2-globulins in blood with simultaneous increase of monoenoic fatty acids in blood and liver tissue. Nerobolyl normalized these patterns at a dose 20 mg/kg, while a dose 5 mg/kg was distinctly less effective.
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Reference: Bogdarin I.A., Effect of anabolic steroid hormones on protein and lipid metabolic indices in thermal injury, Voprosy meditsinskoi khimii, 1979, vol: 25(3), 274-278.
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