Voprosy meditsinskoi khimii (ISSN 0042-8809)

Arachidonic acid biosynthesis in the rat small intestine

   
Staviskiĭ I.M., Gubareva A.E., Alimova E.K., Avastsaturian A.T.
PubMed Id: 452499
Year: 1979 vol: 25  issue:3  pages: 314-318
Abstract: Ability of epithelium of rat small intestine mucose to synthetize arachidonic acid was studied in vivo and in vitro. Linoleic acid and 2-14C-acetate were used as precursors. The fatty acids were fractionated using thin-layer chromatography on silica gel impregnated with AgNO3. The label was incorporated into all the fractions but the highest radioactivity was found in the fraction of arachidonic acid; this suggests that the enzyme systems, carrying out the synthesis of polyenic fatty acids, occur in the mucosa of small intestine.
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Reference: Staviskiĭ I.M., Gubareva A.E., Alimova E.K., Avastsaturian A.T., Arachidonic acid biosynthesis in the rat small intestine, Voprosy meditsinskoi khimii, 1979, vol: 25(3), 314-318.
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