Oxidation of fatty-aromatic aldehydes in liver tissues | 
 
|
| Kholmina G.V., Gorkin V.Z. | | PubMed Id: 36712 | | Year: 1979 vol: 25 issue:3 pages: 322-328 | | Abstract: A protein fraction, which did not contain NADP [or NADPH]-dependent aldehyde reductase as well as NAD [or NADP]-dependent aldehyde dehydrogenases, but which catalyzed oxidation of fatty-aromatic aldehydes, was isolated from extract of rat liver tissue using ammonium sulfate fractionation combined with gradient syvorptive chromatography on DEAE-Sephadex A-25 [or Molselect DEAE-25], CM-Sephadex C-25 and gel-filtration on Sephadex G-200. Investigations of molecular weight and catalytic properties of the protein fraction obtained enabled to identify it with xanthine oxidase [EC 1.2.3.2]. Aldehyde dehydrogenases as well as xanthine oxidase are involved in oxidation of fatty-aromatic aldehydes to corresponding fatty acids, besides the reduction of the aldehydes to alcohols, catalyzed by aldehyde reductase and alcohol dehydrogenases | | Download PDF: | | Reference: Kholmina G.V., Gorkin V.Z., Oxidation of fatty-aromatic aldehydes in liver tissues, Voprosy meditsinskoi khimii, 1979, vol: 25(3), 322-328. | |
References
|
| |
