Voprosy meditsinskoi khimii (ISSN 0042-8809)

Use of aerosils in activating plasma prekallikrein

Veremeenko K.N., Pogorelaia N.F.
PubMed Id: 38571
Year: 1979 vol: 25  issue:4  pages: 375-379
Abstract: Activation of prekallikreine from human blood plasma was studied using silica (airsiles), which carried functional groups with acidic and alkaline properties on the surface. Prekallikrein was similarly activated by amino- and carboxyairsiles, possessing positive and negative electric charges, respectively, at neutral pH value in a medium. Lysozyme, ribonuclease and spermidine inhibited partially the prekallikreine activation; spermine inhibited it completely.
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Reference: Veremeenko K.N., Pogorelaia N.F., Use of aerosils in activating plasma prekallikrein, Voprosy meditsinskoi khimii, 1979, vol: 25(4), 375-379.