Voprosy meditsinskoi khimii (ISSN 0042-8809)

Effect of flavonoids on aspects of nitrogen metabolism in experimental uremia

   
Sokolova V.E., Liubartseva L.A.
PubMed Id: 473674
Year: 1979 vol: 25  issue:4  pages: 379-382
Abstract: Content of free ammonia and glutamine amide nitrogen was increased but content of protein amide nitrogen was decreased in brain tissue after bilateral nephrectomy of rats causing development an experimental uremia; an increased synthesis of urea and activation of arginase were observed in liver tissue. Flavonoids robinine and hyperine decreased the content of free ammonia, increased the content of glutamine amide nitrogen as well as of protein amide nitrogen in rat brain; robinine decreased slightly the urea synthesis and the arginase activity in liver slices of the nephrectomized rats
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Reference: Sokolova V.E., Liubartseva L.A., Effect of flavonoids on aspects of nitrogen metabolism in experimental uremia, Voprosy meditsinskoi khimii, 1979, vol: 25(4), 379-382.
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