Voprosy meditsinskoi khimii (ISSN 0042-8809)

Tryptamine metabolic study in man

Kulinskiĭ V.I., Kononova L.I., Savorenko N.S.
PubMed Id: 473676
Year: 1979 vol: 25  issue:4  pages: 387-392
Abstract: A modified norharmane method was used for estimation of tryptamine in human urine at normal state. Tryptamine excretion did not depend on diuresis. Administration of neomycin did not affect the tryptamine excretion, which is inconsistent with the hypothesis on bacterial origin of the amine. Dynamics of tryptamine excretion was studied after administration of tryptophane, inhibitors of monoamine oxidase and their combinations. Sydnophen and sydnocarb caused hypotryptaminuria. Marked hypertryptaminuria was observed in severe chronic hepatitis and liver cirrhosis.
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Reference: Kulinskiĭ V.I., Kononova L.I., Savorenko N.S., Tryptamine metabolic study in man, Voprosy meditsinskoi khimii, 1979, vol: 25(4), 387-392.