Voprosy meditsinskoi khimii (ISSN 0042-8809)

Polarographic determination of lipid hydroperoxides in the liver of guinea pigs on a varying allowance of ascorbic acid

   
Gazdarov A.K., Gazdarova I.N.
PubMed Id: 494534
Year: 1979 vol: 25  issue:5  pages: 524-527
Abstract: As shown by polarographic method, administration of high doses of ascorbic acid into guinea pigs (100 mg per 100 g of body weight) within two weeks led to a distinct increase (2-fold) in concentration of endogenous peroxides in liver tissue. Maintaining of the animals on a diet, deficient in vitamin C, within 4 weeks (scorbutic animals) was accompanied by 1.6-fold decrease in content of lipid peroxides in liver tissue as compared with control group.
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Reference: Gazdarov A.K., Gazdarova I.N., Polarographic determination of lipid hydroperoxides in the liver of guinea pigs on a varying allowance of ascorbic acid, Voprosy meditsinskoi khimii, 1979, vol: 25(5), 524-527.
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