Voprosy meditsinskoi khimii (ISSN 0042-8809)

Mechanism of the change in energy and electrolyte metabolism in the respiratory musculature in experimental botulism

   
Morrison V.V.
PubMed Id: 516537
Year: 1979 vol: 25  issue:6  pages: 749-752
Abstract: Distinct decrease in concentrations of creatine phosphate and K+ was observed in various respiratory muscles of cat in generalized botulism, accompanied by the syndrom of asphyxia. Content of glycogen and Na+ was unaltered in these cases. In local botulinic paralysis concentrations of creatine phosphate, glycogen and K+ were decreased in the respiratory muscles. Accumulation of Na+ was observed in diaphragm and intercostal muscles. Content of K+ and creatine phosphate was partially restored in respiratory muscles after intraperitoneal administration of guanidine HCl/50 mg/kg of body weight/
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Reference: Morrison V.V., Mechanism of the change in energy and electrolyte metabolism in the respiratory musculature in experimental botulism, Voprosy meditsinskoi khimii, 1979, vol: 25(6), 749-752.
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