Voprosy meditsinskoi khimii (ISSN 0042-8809)

Mechanism of the change in electrolyte and carbohydrate metabolism in the submandibular salivary gland in experimental botulism in rats

   
Mikhaĭlov V.V., Rusanova A.G.
PubMed Id: 7368635
Year: 1980 vol: 26  issue:1  pages: 99-104
Abstract: Content of lactic and pyruvic acids, glycogen, sodium and potassium ions are well as the total LDH activity and its isoenzyme spectrum were not distinctly altered, when secretion of salivary glands was inhibited by administration of botulinic toxin into rats (within 48 hrs after the toxin treatment). But within 14 days the following alterations were observed in the impaired salivary glands: decrease in content of glycogen and potassium, increase in concentration of lactic and pyruvic acids, elevation in total LDH activity and change in its isoenzyme spectrum (increase in content of the fractions responsible for regulation of anaerobic metabolism).
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Reference: Mikhaĭlov V.V., Rusanova A.G., Mechanism of the change in electrolyte and carbohydrate metabolism in the submandibular salivary gland in experimental botulism in rats, Voprosy meditsinskoi khimii, 1980, vol: 26(1), 99-104.
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